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Nevertheless, since GSH cannot be administered directlybecause of its insufficient absorption, stability and solubilityanalogues have been obtained, through modifications at the -glutamyl, cysteine and glycine moieties, and/or the functionalisation of the central cysteine, that are able to inhibit the activity of GSTs 69,87,105

Caloric restriction mimicry: Some investigators have noted that the metabolic effects of glutathione repletion in older adults improved insulin sensitivity, reduced inflammation, enhanced mitochondrial function overlap substantially with known benefits of caloric restriction, suggesting that glutathione deficiency may partly mediate the metabolic decline of aging [10][11]

Glutathione causes a massive and selective induction of plant defense genes

Algal derivatives (phycocyanin and fucoidan) in their drinking water at concentrations of 20 or 40 mg/L significantly reduced Yolk cholesterol in Japanese quails 46

Tryptophan in health and disease