If you are considering peptide therapy, a consultation with the Formation team is the right place to start
this dose also provoked the largest percentage of weight loss though the once-weekly injectable dose of semaglutide at 1 mg was similarly effective.35 Cardiovascular Protection In addition to blood glucose and weight loss benefits, GLP-1s have shown effectiveness in improving cardiovascular outcomes and reducing the risk of major cardiovascular events.36 The SELECT trial showed that semaglutide 2.4 mg weekly significantly reduced major adverse cardiovascular events, heart failure-related hospitalizations, cardiovascular deaths, and all-cause mortality in adults with overweight or obesity and established CVD, including those with and without heart failure
Injecting in the evening means peak effects may occur during sleep, which some people prefer because they sleep through the worst of the nausea, though nighttime diarrhea episodes can obviously disrupt sleep
We monitor for plateaus and address them early
Proc Natl Acad Sci USA 81:50075011 Migoya E, Miller J, Luo W-L et al (2010) Sitagliptin and metformin increase active GLP-1 by complementary mechanisms in treatment-nave patients with type 2 diabetes
The 20mg/mL configuration (20mg vial with 1mL, or 30mg vial with 1.5mL) is optimal
