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At the expected therapeutic dose of 0.5mg, the discontinuation rate due to side effects was similar to that of the placebo group (32%).In another trial called TIPO-2, which lasted for 14 days, tesofensine was found to reduce the desire to eat and increase feelings of fullness in obese patients

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Bio-computation can optimize these aptamers, modeling and testing them through computational docking (70) by a compilation technology introduced by Biogenes Technologies called APTCAD shown in Figure 4

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